Genetic variation on chromosome 16 is associated with abdominal aortic aneurysm
نویسندگان
چکیده
منابع مشابه
A variant in LDLR is associated with abdominal aortic aneurysm.
BACKGROUND Abdominal aortic aneurysm (AAA) is a common cardiovascular disease among older people and demonstrates significant heritability. In contrast to similar complex diseases, relatively few genetic associations with AAA have been confirmed. We reanalyzed our genome-wide study and carried through to replication suggestive discovery associations at a lower level of significance. METHODS A...
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Dear Editor,Abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. The incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positive...
متن کاملIs abdominal aortic aneurysm familial?
suppression of cell mediated immunity. Aflatoxins were detected more commonly in urine from users in The Netherlands than from those in ,Merseyside. Aflatoxin B1, the most toxic aflatoxin, was detected in eight specimens from The Netherlands but only one from Merseyside; the most common aflatoxin detected in the specimens from Merseyside was aflatoxin MI, a less toxic derivative of B1. These va...
متن کاملA Variant in LDLR is Associated with Abdominal Aortic Aneurysm Running title: Bradley et al.; LDLR and Abdominal Aortic Aneurysm
Declan T. Bradley, MB ChB, MA, PhD*; Anne E. Hughes, PhD*; Stephen A. Badger, MCh, MD; Gregory T. Jones, PhD; Seamus C. Harrison, MD; Benjamin J. Wright, PhD; Suzannah Bumpstead, BSc; Annette F. Baas, PhD; Solveig Gretarsdottir, PhD; Kevin Burnand, MBBS, MS; Anne H. Child, MD; Rachel E. Clough, PhD; Gillian Cockerill, PhD; Hany Hafez, MB BCh, PhD; D. Julian A. Scott, MD; Robert A.S. Ariëns, PhD...
متن کاملFamilial abdominal aortic aneurysm is associated with more complications after endovascular aneurysm repair.
OBJECTIVE A familial predisposition to abdominal aortic aneurysms (AAAs) is present in approximately one-fifth of patients. Nevertheless, the clinical implications of a positive family history are not known. We investigated the risk of aneurysm-related complications after endovascular aneurysm repair (EVAR) for patients with and without a positive family history of AAA. METHODS Patients treat...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 1991
ISSN: 0741-5214
DOI: 10.1016/0741-5214(91)90207-b